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Novel patent-pending siRNA modifications permit studies in cell types that are very difficult to transfect. Self-delivering Accell siRNA enters cells without the need for transfection reagents, virus, or electroporation.
Numerous publications cite successful gene silencing in primary cortical and hippocampal neurons, neuroblastoma cell lines, organotypic brain slices, and in vivo rat brain.
Efficient delivery of
Accell siRNA in primary
rat cortical neurons
Buy any gene-specific Accell siRNA reagent and receive a second of equal or lesser value FREE!†
†To redeem, add two or more qualifying Accell siRNA reagents to your order and enter the promotion code ACCELLBG.Offer does not apply to Set of 4 Upgrade.Offers cannot be combined and are valid until December 31, 2012. Offer may not be applied to past orders.
‡These are generic product identifiers. Actual catalog numbers are gene specific.
Confocal microscopy (Zeiss LSM 510) reveals virtually all neurons are positive for uptake of Accell GAPD Red Control siRNA. Scale bar 10 μm.